| 书目名称 | Proteoglycans in Stem Cells |
| 副标题 | From Development to |
| 编辑 | Martin Götte,Karin Forsberg-Nilsson |
| 视频video | |
| 概述 | State-of-the-art compendium on the role of proteoglycans and glycosaminoglycans during development and in cancer.Explores new directions for novel therapeutic and biotechnological applications in stem |
| 丛书名称 | Biology of Extracellular Matrix |
| 图书封面 |  |
| 描述 | .This book provides a state-of-the-art compendium on the role of proteoglycans and glycosaminoglycans during development and in cancer. It also suggests directions for novel therapeutic and biotechnological applications in stem cell biology. . Proteoglycans and glycosaminoglycans, as part of the extracellular matrix, are multifunctional modulators of growth factor, cytokine, integrin and morphogen signaling, which determine both self-renewal, senescence and/or differentiation of stem cells during development. Since proteoglycans modulate cell adhesion and migration they are important organizers of the extracellular matrix within the proper stem cell niche. A malfunctioning of proteoglycans and glycosaminoglycans contributes to the cancer stem cell phenotype, which is linked to therapeutic resistance and recurrence in malignant disease. . This book is essential reading for anyone interested in the extracellular matrix and its role in development..The series .Biology of Extracellular Matrix. is published in collaboration with the American Society for Matrix Biology.. |
| 出版日期 | Book 2021 |
| 关键词 | Extracellular Matrix; Proteoglycans; Glycosaminoglycans; Development; Cancer; Stem Cells; Tumor; Differenti |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-73453-4 |
| isbn_softcover | 978-3-030-73455-8 |
| isbn_ebook | 978-3-030-73453-4Series ISSN 0887-3224 Series E-ISSN 2191-1959 |
| issn_series | 0887-3224 |
| copyright | Springer Nature Switzerland AG 2021 |
发表于 2025-3-21 18:07:04
