书目名称 | Protein-Ligand Interactions |
副标题 | Methods and Applicat |
编辑 | Mark A. Williams,Tina Daviter |
视频video | |
概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | .Proteins are the cell’s workers, their messengers and overseers. In these roles, proteins specifically bind small molecules, nucleic acid and other protein partners. Cellular systems are closely regulated and biologically significant changes in populations of particular protein complexes correspond to very small variations of their thermodynamics or kinetics of reaction. Interfering with the interactions of proteins is the dominant strategy in the development of new pharmaceuticals. .Protein Ligand Interactions: Methods and Applications, Second Edition. provides a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins. From the initial discovery of natural substrates or potential drug leads, to the detailed quantitative understanding of the mechanism of interaction, all stages of the research process are covered with a focus on those techniques that are, or are anticipated to become, widely accessible and performable with mainstream commercial instrumentation. Written in the highly successful .Methods in Molecular Biology. series format, chapters contain introductions to their respective topics, lists of the necessary mat |
出版日期 | Book 2013Latest edition |
关键词 | kynetics; ligand discovery; membrane system; spectroscopy; thermodynamics |
版次 | 2 |
doi | https://doi.org/10.1007/978-1-62703-398-5 |
isbn_softcover | 978-1-4939-5873-3 |
isbn_ebook | 978-1-62703-398-5Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science+Business Media New York 2013 |