书目名称 | Protein Tyrosine Phosphatases in Cancer | 编辑 | Benjamin G. Neel,Nicholas K. Tonks | 视频video | | 概述 | Discusses the current status of PTP-based therapeutics.Examines phosphatase-independent roles for PTEN in Cancer.Explores dual specificity phosphatases in cancer | 图书封面 |  | 描述 | This book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine phosphorylation, feature in cancer cell biology. The expertly authored chapters will first review the general features of the PTP superfamily, including their overall structure and enzymological properties; use selected examples of individual PTP superfamily members, to illustrate emerging data on the role of PTPs in cancer; and will review the current status of PTP-based drug development efforts..Protein Tyrosine Phosphatases in Cancer,.from renowned researchers Benjamin Neel. .and Nicholas Tonks, is invaluable reading for researchers in oncology, stem cell signaling,and biochemistry. . | 出版日期 | Book 2016 | 关键词 | Phosphatase; SHP2; TC-PTP; PTEN; CdC25 | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-3649-6 | isbn_softcover | 978-1-4939-8106-9 | isbn_ebook | 978-1-4939-3649-6 | copyright | Springer Science+Business Media, LLC 2016 |
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