书目名称 | Protein Modifications in Pathogenic Dysregulation of Signaling |
编辑 | Jun-ichiro Inoue,Mutsuhiro Takekawa |
视频video | http://file.papertrans.cn/762/761715/761715.mp4 |
概述 | Discusses cutting-edge methodologies and integrated interdisciplinary approaches to the study of post-translational modifications that regulate critical cellular signal pathways.Draws together recentl |
图书封面 |  |
描述 | This book is devoted to recent advances in analysis of the molecular basis and dynamics of post-translational modifications (PTMs) of proteins for a comprehensive understanding of their key roles in cell signaling networks and diverse biological processes, and their perturbation in a variety of life-threatening diseases such as cancer and inflammatory diseases. The book includes research regarding PTMs and methods of their investigation derived from interdisciplinary collaborations between leading scientists in the fields of molecular, medical, proteomic, structural, and mathematical biology. This book consists of four sections. The first part focuses on recent advances in procedures for analysis of PTMs and cell signaling. The second part is devoted to mathematical simulation of signal transduction pathways and of the formation of protein complexes in living cells. The third part deals with structural and functional analyses of proteins involved in the regulation of PTMs and cell signaling. The fourth part describes cutting-edge findings regarding critical signal transduction pathways and their dysregulation in human diseases. This book is aimed at both established scientists and |
出版日期 | Book 2015 |
关键词 | Cell signaling; Interdisciplinary collaboration; Molecular pathophysiology; Post-translational modifica |
版次 | 1 |
doi | https://doi.org/10.1007/978-4-431-55561-2 |
isbn_softcover | 978-4-431-56253-5 |
isbn_ebook | 978-4-431-55561-2 |
copyright | Springer Japan 2015 |