书目名称 | Protein Misfolding Diseases | 副标题 | Methods and Protocol | 编辑 | Cláudio M. Gomes | 视频video | | 概述 | Includes cutting-edge methods and protocols for the study of protein folding diseases.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | This detailed book gathers a broad collection of experimental approaches to assist researchers in setting up different methods to investigate protein conformational disorders. Beginning with a section on assays focusing on biophysical approaches to study protein (mis)folding, the volume continues with sections on cellular and proteostasis assays as well as assays for protein folding correction and recovery, combining methods such as thermal shift assays, .in silico. improvement of protein solubility, and compound screening, an important area of research as it may open avenues for therapeutic strategies. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. .Authoritative and practical, .Protein Misfolding Diseases:Methods and Protocols. serves as an ideal guide for researchers seeking to advance our knowledge of protein conformational disorders.. | 出版日期 | Book 2019 | 关键词 | Protein biophysics; Chaperonopathies; Proteostasis; Protein folding diseases; Conformational disorders; A | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-8820-4 | isbn_softcover | 978-1-4939-9396-3 | isbn_ebook | 978-1-4939-8820-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2019 |
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