| 书目名称 | Progress in the Chemistry of Organic Natural Products 115 | | 编辑 | A. Douglas Kinghorn,Heinz Falk,Verena M. Dirsch | | 视频video | | | 概述 | Written by recognized authorities in the field.Provides comprehensive and up-to-date reviews on the topic.Part of a well-known series | | 丛书名称 | Progress in the Chemistry of Organic Natural Products | | 图书封面 |  | | 描述 | This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca.2+. ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer. | | 出版日期 | Book 2021 | | 关键词 | Total synthesis; decanolides; thapsigargin; cryptolepine; Lead compound in drug development; natural prod | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-030-64853-4 | | isbn_softcover | 978-3-030-64855-8 | | isbn_ebook | 978-3-030-64853-4Series ISSN 2191-7043 Series E-ISSN 2192-4309 | | issn_series | 2191-7043 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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发表于 2025-3-21 18:36:12
