书目名称 | Polyploidization and Cancer |
编辑 | Randy Y. C. Poon |
视频video | |
概述 | Gives overview on subjects related to polyploidization and cancer.Examples of polyploidization including hematopoietic cells and liver cells.State-of-the-art methodologies on how ploidy can be measure |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overviewsubjects relating to polyploidization and cancer. |
出版日期 | Book 2010 |
关键词 | Chromosom; DNA; carcinogenesis; cell; cytokines; esophagus; laser; liver; proteins; tumor; tumorigenesis |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4419-6199-0 |
isbn_softcover | 978-1-4939-5143-7 |
isbn_ebook | 978-1-4419-6199-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |