书目名称 | Plasma Cell Dyscrasias |
编辑 | Aldo M. Roccaro,Irene M. Ghobrial |
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概述 | Documents the state of the art in the biology and treatment of plasma cell malignancies.Discusses advances in understanding of the responsible molecular mechanisms.Written by leading experts in the fi |
丛书名称 | Cancer Treatment and Research |
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描述 | This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström’s macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias. |
出版日期 | Book 2016 |
关键词 | Bone marrow microenvironment; Genetics; Multiple Myeloma; Plasma cell dyscrasias; Therapies |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-40320-5 |
isbn_softcover | 978-3-319-82078-1 |
isbn_ebook | 978-3-319-40320-5Series ISSN 0927-3042 Series E-ISSN 2509-8497 |
issn_series | 0927-3042 |
copyright | Springer International Publishing Switzerland 2016 |