| 书目名称 | Phospholipid Metabolism in Apoptosis | | 编辑 | Peter J. Quinn,Valerian E. Kagan | | 视频video | | | 丛书名称 | Subcellular Biochemistry | | 图书封面 |  | | 描述 | The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. The number of publications on the topic has increased from nothing in the early 1980s to more than 10,000 papers annually today. It is now well recognized that apoptosis is essential in many aspects of normal development and is required for maintaining tissue homeostasis. The idea that life requires death seems somewhat paradoxical, but cell suicide is essential for an animal to survive. For example, without selective destruction of “non-self” T cells, an animal would lack immunity. Similarly, meaningful neural connections in the brain are whittled from a mass of cells. Further, developmental cell remodeling during tissue maturation involves programmed cell death as the major mechanism for functional and structural safe transition of undifferentiated cells to more specialized counterparts. Apoptosis research, with roots in biochemistry, developmental and cell biology, genetics, and immunology, embraces this long-ignored natural law. Failure to properly regulate apoptosis can have catastrophic consequences. Cancer and many diseases (AID | | 出版日期 | Book 2002 | | 关键词 | Lipid; Oxidation; biosynthesis; metabolism; molecular mechanisms; regulation | | 版次 | 1 | | doi | https://doi.org/10.1007/b105359 | | isbn_softcover | 978-1-4757-8216-5 | | isbn_ebook | 978-0-306-47931-1Series ISSN 0306-0225 Series E-ISSN 2542-8810 | | issn_series | 0306-0225 | | copyright | Springer Science+Business Media New York 2002 |
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发表于 2025-3-21 19:52:39
