| 书目名称 | Phosphoinositides and Disease |
| 编辑 | MARCO FALASCA |
| 视频video | http://file.papertrans.cn/747/746357/746357.mp4 |
| 概述 | A comprehensive overview of the current state of research and where the field of research is progressing to.A useful tool for understanding how inositol signaling is used to target complex human disea |
| 丛书名称 | Current Topics in Microbiology and Immunology |
| 图书封面 |  |
| 描述 | Phosphoinositides (PIs) are minor components of cellular membranes that play critical regulatory roles in several intracellular functions. This book describes the main enzymes regulating the turnover of each of the seven PIs in mammalian cells, some of their intracellular functions and some evidence of their involvement in human diseases. Due to the complex inter-relation between the distinct PIs and the plethora of functions that they can regulate inside a cell, this book is not meant to be a comprehensive coverage of all aspects of PIs signalling but rather an overview on the current state of the field and where it could go from here. Phosphoinositide and inositol phosphates interact with and modulate the recruitment and activation of key regulatory proteins and in doing so control diverse functions including cell growth and proliferation, apoptosis, cytoskeletal dynamics, insulin action, vesicle trafficking and nuclear function. Initially, inositide signaling was limited to the PLCpathway; however, it is now clear that all the seven phosphoinositides and more than 30 different inositol phosphates likely have specific signaling functions. Moreover there is a growing list of prote |
| 出版日期 | Book 2012 |
| 关键词 | Inositol Phosphates; Phosphoinositides |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-94-007-5025-8 |
| isbn_softcover | 978-94-007-9426-9 |
| isbn_ebook | 978-94-007-5025-8Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | Springer Science+Business Media Dordrecht 2012 |
|Archiver|手机版|小黑屋|
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