书目名称 | Phosphatase Modulators |
编辑 | José Luis Millán |
视频video | |
概述 | Serves as a "how to" manual for the initiation of drug discovery efforts.Provides step-by-step detail essential for reproducible results.Contains key tips and implementation advice from the experts |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | .Driving further the research on mammalian alkaline phosphatase structure and function, .Phosphatase Modulators. collects expert contributions into one “how to” manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making “go/no-go” decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful .Methods in Molecular Biology. series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results.. .Step-by-step and practical, .Phosphatase Modulators. offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts. |
出版日期 | Book 2013 |
关键词 | Drug discovery; Medicinal chemistry; Pharmaceuticals; Probe development; TNAP; Tissue-nonspecific alkalin |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-62703-562-0 |
isbn_softcover | 978-1-4939-6031-6 |
isbn_ebook | 978-1-62703-562-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science+Business Media, LLC 2013 |