| 书目名称 | Pharmacology of Neurotransmitter Release |
| 编辑 | Thomas C. Südhof,Klaus Starke |
| 视频video | |
| 概述 | Includes supplementary material: |
| 丛书名称 | Handbook of Experimental Pharmacology |
| 图书封面 |  |
| 描述 | .It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the book’s second part, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process. These include ligand-gated ion channels and presynaptic G-protein-coupled receptors. The targets of presynaptic receptors within the exocytosis cascade, and their therapeutic potential, are subjects addressed in the majority of chapters.. |
| 出版日期 | Book 2008 |
| 关键词 | Cannabinoid; Exocytosis; Neurotransmitter Release; Presynaptic autoreceptors; Synaptic plasticity; adenos |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-540-74805-2 |
| isbn_softcover | 978-3-642-09424-8 |
| isbn_ebook | 978-3-540-74805-2Series ISSN 0171-2004 Series E-ISSN 1865-0325 |
| issn_series | 0171-2004 |
| copyright | Springer-Verlag Berlin Heidelberg 2008 |
发表于 2025-3-21 17:48:39
