| 书目名称 | Peroxisome Proliferator-Activated Receptors (PPARs) | | 副标题 | Methods and Protocol | | 编辑 | Mostafa Z. Badr,Jihan A. Youssef | | 视频video | | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts..Includes supplementary materi | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology but differ in function, tissue distribution and ligand specificity. PPARs play critical roles as regulators of numerous physiological as well as pathophysiological pathways, and efforts are currently underway to fully characterize their functioning and to develop safer and more effective PPAR modulators to treat a myriad of diseases and conditions. In .Peroxisome proliferator-Activated Receptors: Methods and Protocols., renowned experts in the PPAR arena provide detailed protocols for investigating these receptors. Chapters contain methods ranging from the cloning of receptors to their knockdown, to protocols exploring posttranslational modifications of PPARs and coactivators, as well as receptor subcellular localization. Also assembled are methods to evaluate the involvement of these receptors in behavior functions, an emerging facet in PPAR research. Written in the successful .Methods in Molecular Biology™. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocol | | 出版日期 | Book 2013 | | 关键词 | PPAR activity; gene targeting; genotyping; physiological pathways; posttranslational modifications | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-62703-155-4 | | isbn_softcover | 978-1-4939-6257-0 | | isbn_ebook | 978-1-62703-155-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media New York 2013 |
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发表于 2025-3-21 18:02:38
