书目名称 | Patient-Specific Modeling of the Cardiovascular System | 副标题 | Technology-Driven Pe | 编辑 | Roy C.P. Kerckhoffs | 视频video | | 概述 | First book to focus on patient-specific modeling of the heart.This book covers the design of a variety of patient-specific models within the cardiovascular system in computational biology.Focus on the | 图书封面 |  | 描述 | Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial press | 出版日期 | Book 2010 | 关键词 | Computational Biology; Heart; Kerckhoffs; Modeling; calculus; cardiovascular; computed tomography (CT); dia | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4419-6691-9 | isbn_softcover | 978-1-4899-8242-1 | isbn_ebook | 978-1-4419-6691-9 | copyright | Springer Science+Business Media, LLC 2010 |
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