| 书目名称 | Patient-Derived Xenografts |
| 副标题 | Methods and Protocol |
| 编辑 | Mohamed I. Saad |
| 视频video | |
| 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | This detailed volume explores the dynamic landscape of patient-derived xenograft (PDX) generation and applications. After a few chapters examining the evolution of PDXs, tracing their roots and contextualizing their significance in the broader narrative of cancer research, the book continues with methodologies for generating PDXs from diverse clinical tissue samples as well as for utilizing PDXs in various specific cancer types. From the development of humanized PDX models to the exploration of protein expression through advanced techniques including multiplex immunohistochemistry, Western blotting, and immunoprecipitation, the chapters offer a comprehensive toolkit for researchers and clinicians alike. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and practical, .Patient-Derived Xenografts: Methods and Protocols. serves as an ideal interdisciplinary guide for understanding the intricate processes that underscore translat |
| 出版日期 | Book 2024 |
| 关键词 | PDXs; Cancer therapeutics; Translational cancer research; Clinical tissue samples; Cancer types; Protein |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-0716-3858-3 |
| isbn_softcover | 978-1-0716-3860-6 |
| isbn_ebook | 978-1-0716-3858-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
发表于 2025-3-21 18:04:20
