书目名称 | Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism |
编辑 | Jean Pieters,John D. McKinney |
视频video | |
概述 | A stimulus for the further exploration of the intricate biology of Mycobacterium tuberculosis and its interaction with the host.Written by respected experts from different disciplines.Richly illustrat |
丛书名称 | Current Topics in Microbiology and Immunology |
图书封面 |  |
描述 | .Mycobacterium tuberculosis. is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of .M. tuberculosis. as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of .M. tuberculosis. in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host’s innate immune defence mechanisms..In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of .M. tuberculosis., ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts.. |
出版日期 | Book 2013 |
关键词 | Drug resistance; Host-pathogen interaction; Macrophages; Microbial infection; Tuberculosis |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-40232-6 |
isbn_softcover | 978-3-662-52142-7 |
isbn_ebook | 978-3-642-40232-6Series ISSN 0070-217X Series E-ISSN 2196-9965 |
issn_series | 0070-217X |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |