| 书目名称 | Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations |
| 编辑 | Ellen Hsu,Louis Du Pasquier |
| 视频video | |
| 概述 | Provides state-of-the-art reviews on host-pathogen interactions.Offers comprehensive information on the immunological processes involved in pathogen defense in different organisms.Written by internati |
| 丛书名称 | Results and Problems in Cell Differentiation |
| 图书封面 |  |
| 描述 | .This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens has given rise to corresponding processes that produce molecular variation. Whether in mollusks or human beings, various host somatic mechanisms have evolved independently, providing responses to counter rapidly-changing pathogens. The pathways they utilize can include non-heritable changes involving RNA and post-translational modifications, or changes that produce somatic DNA recombination and mutation. For infectious organisms such as protozoans and flatworms, antigenic variation is central to their survival strategy. Evolving the ability to evade the host immune system not only increases their chances of survival but is also necessary for successful re-infection within the host population.. |
| 出版日期 | Book 2015 |
| 关键词 | Antibody repertoire; Antigenic variation; Host somatic mechanism; Host-pathogen interactions; Lymphocyte |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-20819-0 |
| isbn_softcover | 978-3-319-37182-5 |
| isbn_ebook | 978-3-319-20819-0Series ISSN 0080-1844 Series E-ISSN 1861-0412 |
| issn_series | 0080-1844 |
| copyright | Springer International Publishing Switzerland 2015 |
发表于 2025-3-21 16:57:28
