| 书目名称 | Patch-Clamp Methods and Protocols |
| 编辑 | Marzia Martina,Stefano Taverna |
| 视频video | |
| 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | .Since its inception, patch-clamp has continued to be widely considered the gold standard method to record ion channel activity. .Patch-Clamp Methods and Protocols, Second Edition., provides a comprehensive collection of new techniques for the development of automated, high-throughput screening systems for pharmacological evaluation, the use of various patch-clamp configurations together with novel molecular biological and imaging methodologies and enhanced stimulation protocols and perfusion systems. Divided into sections on pharmacology, physiology and biophysics, the chapters cover methods to generate more physiologically relevant conditions for drug application and screening technologies, recently developed applications such as optogenetic stimulation, advances in whole-cell recordings in freely-moving animals and novel technologies to create custom microelectrodes designed for reducing the access resistance and improving the rate of molecular diffusion. Patch-clamp is an indispensable technique for conducting pharmacological, physiological and biophysical research aimed at understanding crucial aspects of cellular and network function. Written in the successful Methods in Mole |
| 出版日期 | Book 2014Latest edition |
| 关键词 | biophysics; dynamic clamp; patch-clamp; pharmacology; physiology |
| 版次 | 2 |
| doi | https://doi.org/10.1007/978-1-4939-1096-0 |
| isbn_softcover | 978-1-4939-5414-8 |
| isbn_ebook | 978-1-4939-1096-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | Springer Science+Business Media New York 2014 |
发表于 2025-3-21 19:26:56
