| 书目名称 | PI3K and AKT Isoforms in Immunity |
| 副标题 | Mechanisms and Thera |
| 编辑 | Margarita Dominguez-Villar |
| 视频video | |
| 概述 | Gives a detailed introduction into the biology of the three PI3K classes.Discusses the role of AKT and PI3K isoforms in immune cells and immune-mediated diseases.Highlight the latest advances in the d |
| 丛书名称 | Current Topics in Microbiology and Immunology |
| 图书封面 |  |
| 描述 | .This book provides an essential overview of the role of phosphoinositide-3-phosphate kinase (PI3K) isoforms in modulating the function of immune system cells and their involvement in disease..PI3K is a family of kinases involved in basic cellular processes such as proliferation, migration and cell death. Recent work has highlighted the multiple roles of PI3K classes and subunits and their involvement in the immune response to the body’s own and foreign antigens and diseases such as cancer and autoimmunity. This book offers a detailed introduction to the biology of the three PI3K classes, followed by an extensive discussion of the diverse roles of AKT and PI3K isoforms in immune cells. Based on this knowledge, it subsequently explains in more detail how specific isoforms are connected to immune-mediated diseases. The book concludes by highlighting the latest advances in the production of isoform-specific inhibitors and their use in various human diseases..This book is intended as a reference guide for students and researchers interested in the multifaceted aspects of PI3K biology.. |
| 出版日期 | Book 2022 |
| 关键词 | PI3K isoforms; AKT isoforms; Therapy; Immunology; Immune response; serine/threonine kinase; Phosphoinositi |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-031-06566-8 |
| isbn_softcover | 978-3-031-06568-2 |
| isbn_ebook | 978-3-031-06566-8Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 16:45:40
