书目名称 | Oxidative Stress in Cardiovascular-Metabolic Diseases |
编辑 | Ali Hussein Eid,Firas Kobeissy,Ahmed F. El-Yazbi |
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概述 | Discusses preventive measures that can combat ROS-induced cardiovasclo-metabolic disease.Pays attention to the interplay between aging and oxidative stress in the context of cardiovasculo-metabolic di |
丛书名称 | Oxidative Stress in Applied Basic Research and Clinical Practice |
图书封面 |  |
描述 | .The book dissects the role of oxidative stress in the pathogenesis of the leading causes of global morbidity and mortality, i.e. cardiovascular and metabolic diseases. The chapters discuss topics related to the role reactive oxygen species (ROS) play in hypertension, atherosclerosis, diabetes, obesity and related pathologies. One chapter discusses the clinical efficacy and safety considerations of GLP-1 receptor agonists and SGLT-2 inhibitors in obesity management and the associated cardiovascular complications. Another chapter discusses the context-dependent roles of matrix metalloproteases, and how their activity can be modulated and utilized for the development of improved drugs for cardiometabolic diseases. Moreover, how ROS and aging interplay to precipitate cardiovasculo-metabolic disease is discussed and highlighted. Similarly, how sex and sepsis interplay in the context of cardiorenal disease is teased out in one of the chapters. Preventive measures that can abrogate ROS-induced cardiovasclo-metabolic disease are discussed and clarified in the hope of reducing such a debilitating battery of diseases. Another chapter is fully dedicated to the roles of ROS in atherosclerosis |
出版日期 | Book 2024 |
关键词 | Oxidative stress; Heart disease; Cardiovascular disease; Obesity; Diabetes; Pathophysiology of cardiovasc |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-031-62131-4 |
isbn_softcover | 978-3-031-62133-8 |
isbn_ebook | 978-3-031-62131-4Series ISSN 2197-7224 Series E-ISSN 2197-7232 |
issn_series | 2197-7224 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |