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Titlebook: Oxidative Stress Biomarkers and Antioxidant Protocols; Donald Armstrong Book 2002 Humana Press 2002

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书目名称Oxidative Stress Biomarkers and Antioxidant Protocols
编辑Donald Armstrong
视频video
概述Includes supplementary material:
丛书名称Methods in Molecular Biology
图书封面Titlebook: Oxidative Stress Biomarkers and Antioxidant Protocols;  Donald Armstrong Book 2002 Humana Press 2002
描述The first protocols book, Free Radical and Antioxidant Protocols (1) was published in late 1998. Sections were divided into three parts, covering selected biochemical techniques for measuring oxidative stress, antioxidant (AOX) activity, and combined applications. In choosing the 40 methods to be included in that book, I realized there were considerably more of equal value than that which we could have presented in a single volume. To produce a comprehensive resource, this book and a third are being compiled to expand coverage of the field. A summary of papers (2) published on this important subject emphasizes the continuing rapid growth in oxidative stress investigations relating to our understanding of biochemical reactions, their relevance to pathophysiological mechanisms, how disease may arise, and how therapeutic intervention may be achieved(3). Although there is some overlap between the categories, the ana- sis shown below illustrates where current studies are concentrated and are almost evenly distributed between free radicals and AOX. Over the last 4 yr, there has been a 55% increase in the number of papers published in the area.
出版日期Book 2002
版次1
doihttps://doi.org/10.1385/1592591736
isbn_softcover978-1-61737-222-3
isbn_ebook978-1-59259-173-2Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 2002
The information of publication is updating

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Hydroxyl and 1-Hydroxyethyl Radical Detection by Spin Trapping and GC-MSing and ESR procedures often has been done using 5,5-dimethylpyrroline N-oxide (DMPO) as the spin trap (.–.). This spin trap very rapidly reacts with OH to produce a stable free radical adduct having a characteristic ESR spectrum (.–.).
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Book 2002cted biochemical techniques for measuring oxidative stress, antioxidant (AOX) activity, and combined applications. In choosing the 40 methods to be included in that book, I realized there were considerably more of equal value than that which we could have presented in a single volume. To produce a c
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Formation of Apolipoprotein AI-AII Heterodimers by Oxidation of High-Density Lipoprotein (“tyrosylated HDL”), one mechanism of phagocyte-mediated oxidation (.), results in a markedly enhanced ability of HDL to promote the mobilization of cholesterol from a variety of cultured cells (.–.). If occurring in vivo, this oxidative modification of HDL may actually enhance its ability to protect against atherosclerosis.
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