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Titlebook: Osteosarcoma; Takafumi Ueda,Akira Kawai Book 2016 Springer Japan 2016 doxorubicin.ifosfamide.limb-salvage surgery.methotrexate.neoadjuvant

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Immunotherapy for Osteosarcoma modalities are required. We have been working on the development and clinical application of immunotherapy for osteosarcoma since 1998. In this chapter, we describe our studies and discussed the future directions of immunotherapy for osteosarcoma.
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Outcome of Treatment for Osteosarcoma of the Extremities Over the Last 20 Years: Report from 11 Refes for osteosarcoma chemotherapy are methotrexate, doxorubicin, and cisplatin, and multi-institutional trials based on these drugs have been conducted in Japan since the 1990s. However, there have been no nationwide data on treatment outcome, especially with regard to survival and prognostic factors.
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Neoadjuvant Chemotherapy Developed in Japanpy and limb-preserving procedure have been developed in the USA since around 1970 and in Japan since around 1980. In addition, histologic evaluation concerned with the rate of necrosis of excised tumors after preoperative chemotherapy has been tried, and it has been reported that patients with highe
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Endoprosthetic Reconstruction for Extremity Osteosarcomatruction following resection of a bone tumor has a history of more than 70 years, and modern endoprosthesis provides intraoperative flexibility to fill the bony defect and structural stability to allow for immediate weight bearing. Although prosthetic reconstruction has become a standard surgical te
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Limb Salvage Surgery for Pelvic Osteosarcomative approach varies according to anatomic location, extent of resection, the patient’s functional demands, and individual surgeon preference. The choice of optimal technique for reconstruction after acetabular tumor resection depends on numerous parameters and includes iliofemoral arthrodesis or ps
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Management of Postoperative Infection After Limb Salvage Surgery in Osteosarcoma Patientsion is approximately ten times higher than that of conventional orthopedic surgery, and the impact of infection on limb survival and functional loss is significant. Due to the paucity of the surrounding soft tissue, the local conditions of limb salvage surgery for osteosarcoma patients and the patho
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