Titlebook: Osteonecrosis of the Femoral Head; A Clinical Casebook Rafael J. Sierra Book 2017 Mayo Foundation for Medical Education and Research 2017 B

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Osteonecrosis and Thrombophilia: Pathophysiology, Diagnosis, and Treatmentn tests revealed heterozygosity for the G20210A prothrombin gene mutation, resistance to activated protein C, and heterozygosity for the factor V Leiden mutation, respectively. In two patients, ages 47 and 54, exogenous testosterone appeared to interact with the prothrombin and factor V Leiden mutat

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Simultaneous Cell Therapy Preserving Surgery and Contralateral Arthroplasty for Bilateral Hip Osteonsty for bilateral osteonecrosis of the femoral head. This is an interesting case of osteonecrosis that is related to sickle cell disease. Sickle cell disease (SCD), also called sickle cell disease anemia (SCA), is an autosomal-recessive disorder due to hemolytic anemia characterized by abnormally sh

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Bilateral Osteonecrosis Associated with Corticosteroid Treatment: Stem Cell Therapy Versus Core Deco This case demonstrates that persistent hip pain, especially with joint movement, tenderness, or reduced range of motion, warrants magnetic resonance imaging because of the association of glucocorticoid therapy with osteonecrosis. The pathognomonic, subchondral crescent sign seen on radiographic exa

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Minimally Invasive Core Decompression Augmented with Concentrated Autologous Mesenchymal Stem Cells core decompression alone is insufficient to heal the ON site and prevent progression and collapse. Recently, bone marrow has been aspirated from the iliac crests of patients, concentrated, and injected into the areas of ON. The bone marrow concentrate (BMC) contains mesenchymal stem cells, which ha

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Osteonecrosis of the Femoral Headnagement is rarely indicated, whereas core decompression with grafting can be a successful treatment method if used prior to collapse of the femoral head. For cases where subchondral collapse has occurred, total hip arthroplasty (THA) is the treatment of choice.

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Femoral Head Decompression Using the X-REAM® Followed by Autologous Tibial Cancellous Bone Impactionn grafting technique..Our main modification of the original core decompression and impacting grafting technique is more extended removal of the osteonecrotic area of the femoral head and the use of a small incision, using the X-REAM® instrumentation. After necrotic bone removal, autologous cancellou

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Autologous Osteochondral Transfer for Management of Femoral Head Osteonecrosis head. The osteonecrosis was felt to be sequelae of a postoperative hip subluxation. She underwent a hip core decompression at an outside institution for pre-collapse osteonecrosis. However, she progressed to focal collapse of her femoral head. Given her significant pain and wishes to return to an a

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