Titlebook: Osteoimmunology; Yongwon Choi Conference proceedings 2007 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spri

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Maria Grazia Ruocco,Michael Karin both 1999 and 2000, to 90 in 2001, to this year‘s record breaking 136! Counting technical notes, workshops, poster and video submissions, there were over 250 original works submitted to this y978-3-540-44267-7978-3-540-45809-8Series ISSN 0302-9743 Series E-ISSN 1611-3349

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Marina Stolina PhD,Paul J. Kostenuik PhD,William C. Dougall PhD,Lorraine A. Fitzpatrick MD,Debra J.

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The Negative Role of IDS in Osteoclastogenesis,T (Lee and Kim 2003; Boyle, Simonet and Lacey 2003)..It has been shown that TRANCE induces activation and/or induction of transcription factors such as Mitf, PU.1, and NFATc1 (Boyle, Simonet and Lacey 2003; Teitelbaum 2000; Teitelbaum and Ross 2003). Mitf is known to be important for osteoclastogene

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Functional Genetic and Genomic Analysis of Modeled Arthritis,1996) where it has pleiotropic functions such as the induction of joint inflammation, the proliferation of synovial fibroblasts (SFs) (Butler, Piccoli, Hart, et al. 1988), the destruction of cartilage by induction of collagenase (Dayer, Beutler, and Cerami 1985) and inhibition of proteoglycan synthe

artifice

Dexamethsone Suppresses Bone Formation via the Osteoclast,s their capacity to form mineralized bone nodules (Aubin 1999; Purpura, Aubin, and Zandstra 2004). This paradox raises the possibility that glucocorticoid suppression of bone formation, in vivo, reflects, at least in part, the steroid’s targeting intermediary cells, which in turn inhibit the osteobl

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Immunologic Regulation of Bone Development,ld-type osteoblasts. To investigate the origin of the in vivo increase in osteoclasts, Pax5–/– or +/+ spleen cells were cultured with M-CSF and RANKL and multinucleated, TRAP. cells counted. Cells from Pax5–/– spleen produced 5-10 times more osteoclasts than did controls..Tibia from EBF-1–/– mice ha