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Titlebook: Origin and Evolution of the Vertebrate Immune System; Louis Pasquier,Gary W. Litman Book 2000 The Editor(s) (if applicable) and The Author

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发表于 2025-3-21 18:42:56 | 显示全部楼层 |阅读模式
书目名称Origin and Evolution of the Vertebrate Immune System
编辑Louis Pasquier,Gary W. Litman
视频video
概述Includes supplementary material:
丛书名称Current Topics in Microbiology and Immunology
图书封面Titlebook: Origin and Evolution of the Vertebrate Immune System;  Louis Pasquier,Gary W. Litman Book 2000 The Editor(s) (if applicable) and The Author
描述The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop­ ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte­ brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or­ igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo­
出版日期Book 2000
关键词Antigen; Immunsystem; T cell; development; evolution; fish; genes; genetics; histocompatibility; immunoglobul
版次1
doihttps://doi.org/10.1007/978-3-642-59674-2
isbn_softcover978-3-642-64078-0
isbn_ebook978-3-642-59674-2Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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ihm die Themen einer, wie er es nennt, »Philosophie der Psychologie« aber fraglos in den Jahren 1945 bis zu seinem Tod 1951. Insbesondere verdichten sich in dieser Zeit auch Wittgensteins Bemerkungen zu Problemen des Fremdseelischen, die sich in der Frage ausdrücken lassen, wie – und ob! – wir vom
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L. Du Pasquiers undemokratisch. Folgt man dieser Auffassung, so ist es nicht hinnehmbar, eine große Bevölkerungsgruppe – Personen unter 18 Jahren – vom Wahlrecht auszuschließen. Das Bemühen um ein Wahlrecht für Kinder und Jugendliche hat in den vergangenen Jahrzehnten verstärkte Aufmerksamkeit erhalten. Johannes
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vom verborgenen Inneren. Wie gezeigt wird, untergräbt Wittgenstein die dem traditionellen fremdpsychischen Skeptizismus zugrundeliegende epistemische Unterscheidung zwischen Eigen- und Fremdpsyche mit seinem Hinweis auf ›primitive‹ Verhaltensmuster: Dies meint zum einen Wittgensteins Konzept einer E
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New Approaches Towards an Understanding of Deuterostome Immunitybination (V-D-J recombination, class switching and a highly targeted form of gene conversion) have arisen entirely independently in the course of immunoglobulin (Ig) heavy-chain gene evolution. Similar phenomena are virtually unknown in other metazoan genetic systems. Genes that mediate immunity are
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The Antimicrobial Host Defense of ,cytosis and to encapsulation by hemocytes (. 1887; . 1896). Around 1920, a number of independent studies established that insects could be protected against the injection of lethal doses of bacteria by the prior administration of low doses (. 1920; . 1920; . 1918) and that this induced protection wa
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