Titlebook: Origin and Evolution of New Gene Functions; M. Long Book 2003 Springer Science+Business Media Dordrecht 2003 Charles Darwin.Darwin.evoluti

监禁

Origin of new genes: evidence from experimental and computational analyses,. These discoveries revealed the importance of exon shuffling in the origin of new genes. However, only a few cases of exon shuffling were reported from plants and invertebrates, which gave rise to the assertion that the intron-mediated recombination mechanism originated very recently. We focused on

Munificent

充满人

,Birth of ‘human-specific’ genes during primate evolution,d Great Apes. However, anatomical and behavioral traits distinguish . from his closest relatives. I review here several recent studies that address the issue by using different approaches: large-scale sequence comparison (first release) between human and chimpanzee, characterization of recent segmen

多余

gruelling

Modular assembly of genes and the evolution of new functions,s in genomic studies it has now become clear that this mechanism contributed significantly to the evolution of novel biological functions in different evolutionary lineages. Analyses of completely sequenced bacterial, archaeal and eukaryotic genomes has revealed that modular assembly of novel consti

bizarre

BUOY

赌博

Recent evidence for the Exon Theory of Genes,were created through the intron-mediated shuffling of exons. The theory has existed since the late seventies. An uncompromising version of the theory, in which all introns were considered to be ancient, dominated the early work. However, in the late eighties and early nineties evidence arose that at

refraction

先行

Population-genetic models of the fates of duplicate genes,r fate can occur via neofunctionalization wherein one copy acquires a new function or by subfunctionalization wherein the original function of the gene is partitioned across both copies. The relative probabilities of these three different fates involve often very subtle iterations between of populat