Titlebook: Organism Models of Autism Spectrum Disorders; Pierre L. Roubertoux Book 2015 Springer Science+Business Media New York 2015 Autism Spectrum

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Viewing Animal Models for Tuberous Sclerosis Complex in the Light of Evolutiontations seen in human examples of TSC, and whether the nonhuman proteins are accurate models for all the structural and functional features of the human proteins. We also discuss the appropriateness of these organisms as models for human cognitive functions. Current evidence suggests that rat and mo

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Invertebrate Models of Synaptic Transmission in Autism Spectrum Disorderstebrates and invertebrates. Invertebrates are also easy to handle, and most of them are reproduced rapidly in the laboratory, which allows obtaining many individuals to study the effect of mutations and/or environmental factors in behavior. In this chapter, we review the features that make ., ., and

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Epigenetic Factors in Normal and Pathological Neuronal Developmentth neurological pathologies including ASD. In conclusion, epigenetic modifiers play a crucial role in brain development and further research is needed in order to elucidate a large number of pathological processes.

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Serotonin Disturbance in Mouse Models of Autism Spectrum Disordersng, a comprehensive understanding of a causative role or mechanism of action of 5-HT in ASD is still far off. Here, we summarize 5-HT features in ASD and rodent models of the disorder. Serotonergic disturbances in models for ASD will provide a clue to understanding ASD.

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Zebrafish Social Behavior Testing in Developmental Brain Disordersogress made in the rodent literature. Taking into account that no single animal model can recapitulate all aspects of human behaviors impaired in pervasive brain disorders, using zebrafish to complement existing efforts using different models may open up new avenues of discovery not previously explo

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Deficit in Social Relationships and Reduced Field of Interest in Micent communication is explored. Ethology has paid attention to social structures in rodents but measuring the ability to develop social interactions in mice has emerged recently. Different tests are presented and their results are compared. Modeling disruptive behavior is then examined. The second par

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Book 2015sychiatrists and geneticists, as well as behavioral researchers who, realizing how important it is to improve their knowledge through more molecular approaches, are looking for the most suitable organisms..

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