书目名称 | Organelle Contact Sites | 副标题 | From Molecular Mecha | 编辑 | Mitsuo Tagaya,Thomas Simmen | 视频video | | 概述 | Provides a comprehensive description of organelle contact sites (MCS).Assembles the full array of research about the organization and roles of MCS.Presents extensive evidence of the significance of MC | 丛书名称 | Advances in Experimental Medicine and Biology | 图书封面 |  | 描述 | .This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases...MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via these functions, MCS are critical for the survival and the growth of the cell. Owing to that central role in the functioning of cells, MCS dysfunctions lead to important defects of human physiology, influence viral and bacterial infection, and cause disease such as inflammation, type II diabetes, neurodegenerative disorders, and cancer. To approach such a multifaceted topic, this volume assembles a series of chapters dealing with the full array of research about MCS and their respective roles for diseases. Most chapters also introduce the history and the state of the art ofMCS research, which will initiate discussion points for the respective types of MCS for years to come...This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunctio | 出版日期 | Book 2017 | 关键词 | Mitochondria; Mitochondria-associated membrane; Membrane contact sites; Endoplasmic reticulum; Alzheimer | 版次 | 1 | doi | https://doi.org/10.1007/978-981-10-4567-7 | isbn_softcover | 978-981-13-5170-9 | isbn_ebook | 978-981-10-4567-7Series ISSN 0065-2598 Series E-ISSN 2214-8019 | issn_series | 0065-2598 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |
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