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Titlebook: Opioids I; Albert Herz,Huda Akil,Eric J. Simon Book 1993 Springer-Verlag Berlin Heidelberg 1993 Biochemie.Biochemistry.Opiat.Opioid Peptid

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书目名称Opioids I
编辑Albert Herz,Huda Akil,Eric J. Simon
视频video
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Opioids I;  Albert Herz,Huda Akil,Eric J. Simon Book 1993 Springer-Verlag Berlin Heidelberg 1993 Biochemie.Biochemistry.Opiat.Opioid Peptid
描述In 1957 Otto SCHAUMANN, one of the pionieers in pharmacological research on morphine and the first to prepare synthetic opiates, presented a mono­ graph entitled "Morphin und morphiniihnliche Verbindungen" as Volume 12 of the Handbook of Experimental Pharmacology. Now, 35 years later, we are publishing in the same series a new comprehensive volume covering the present status of opioid research. Since that time the topic has expanded enormously. The identification of opioid receptors and the detection of their endogenous ligands were landmarks which opened a new era in opioid research and fertilized the entire field of neurobiology. The rapid develop­ ment of this field is illustrated in the figure, which represents the number of papers published on opioid research since 1970 (searches performed on the MEDLINE data base). 3000 Vl
出版日期Book 1993
关键词Biochemie; Biochemistry; Opiat; Opioid Peptides; Opioider; Opioids; Pharmacology; Pharmakologie; base; endoge
版次1
doihttps://doi.org/10.1007/978-3-642-77460-7
isbn_softcover978-3-642-77462-1
isbn_ebook978-3-642-77460-7Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 1993
The information of publication is updating

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Allosteric Coupling Among Opioid Receptors: Evidence for an Opioid Receptor Complexd observations in the late 1970s and 1980s which are difficult to explain solely on the basis of distinct opioid receptors. Instead, these observations have led to the postulated existence of an opioid receptor complex, composed of μ-, δ- and perhaps κ-binding sites (V. et al. 1982; D’A. and H. 1984; L. and S. 1980b; B.-K. et al. 1990).
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Presence of Endogenous Opiate Alkaloids in Mammalian Tissueseasible to speculate and ask whether morphine, an opiate alkaloid synthesized in a very complex and stereospecific pathway in the poppy plant . (see Fig. 1), or a closely related compound, also existed as an endogenous compound in mammalian body fluids and tissues.
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Book 1993lized the entire field of neurobiology. The rapid develop­ ment of this field is illustrated in the figure, which represents the number of papers published on opioid research since 1970 (searches performed on the MEDLINE data base). 3000 Vl
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