Titlebook: Opioid Dependence; A Clinical and Epide Heath B. McAnally Book 2018 Springer International Publishing AG 2018 Opioid.Dependence.Abuse.Addic

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https://doi.org/10.1007/978-3-319-47497-7Opioid; Dependence; Abuse; Addiction; Risk management

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Understanding the Agent, Part I: Opioid Biology and Basic PharmacologyEndogenous opioids are produced by the body and act as part of a comprehensive homeostatic self-preservation effort geared toward the well-being of the organism. The most salient aspect of this system is acute pain relief, but within seconds, modulating and counter-regulatory effects are initiated t

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Understanding the Agent, Part II: Adverse Effectsidence for both benefit and risk. Opioids remain some of the most dangerous drugs in the therapeutic armamentarium and confer a high degree of morbidity and mortality. Adverse effects of the class affect virtually every physiologic system, including neuropsychiatric, cardiovascular, respiratory, imm

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Best Practices Education, Part I: Pain Physiology, Psychology, and Alternatives to Opioidschology) and the treatment modalities that are best oriented toward those physiologic—and psychological—processes. Pain is the chief reason patients visit physicians, and as such, it is incumbent upon us, regardless of specialty, to understand it. Acute pain usually begins with nociception or sensat

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Best Practices Education, Part II: Evidence for and Against Opioid Therapy remain a prevalent therapeutic modality for a reason: They possess significant analgesic effects across a wide spectrum of painful conditions. Often referred to as “broad-spectrum analgesics,” they reduce nociception and perception and enhance descending modulation with time-tested efficacy. Mounti

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Best Practices Education, Part III: Regulatory and Advisory Issues Related to Opioid Therapy for Paital level, both state and federal government have developed laws regarding opioid prescription to minimize the risk of diversion while preserving the physician’s privilege of providing these powerful medications to the right patients in the right manner. The prescription of opioids for pain, whether