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Titlebook: Ophthalmic Drug Delivery; Biopharmaceutical, T Marco Fabrizio Saettone,Massimo Bucci,P. Speiser Conference proceedings 1987 Springer Scienc

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P. SpeiserThemen der Umweltgeschichte.Erläutert umwelthistorisches Arb.Dieses Buch behandelt die historischen Voraussetzungen, die zum heutigen Zustand der Ökosysteme unter menschlichem Einfluss geführt haben. Es befasst sich mit den Voraussetzungen und Grundannahmen, auf denen die Rezeptions- und Rekonstrukt
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Factors Influencing the Retention of Ophthalmic Solutions on the Eye Surface,n from the eye surface. Reflex tears and reflex blinking are often elicited by different properties of the instilled solutions, such as the instilled volume, the osmolality, the pH and viscosity of the solution, and also by the physical and chemical properties of the drugs and the adjuvants present.
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Latices and Thermosensitive Gels as Sustained Delivery Systems to the Eye,is the use of carefully selected pH-sensitive polymeric materials dispersed in water in the nanometer size range as carriers or polymers with interesting sol-gel transition behavior. These two systems have been formulated and further investigated in order to slow down the extremely rapid drug exchan
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Contact Lenses as Therapeutic Systems,ntact lenses, by shielding the epithelium from the abrasive action of the lids, may avoid mechanical disruption of the ocular surface and aid its healing. Hydrophilic materials, acting as a fluid reservoir, are useful in dry eye syndromes when used in conjunction with frequent artificial tears insti
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Effect of Contact Lens Solutions on the Functional Morphology of the Cornea,surface is finely irregular, with microvilli and microplicae, and an absorbed layer of the tear film. The integrity of the precorneal film plays a key role in the optical quality of the corneal surface. Topically applied ophthalmic medications or contact lens solutions produce transient concentratio
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Pharmacokinetics and Biopharmaceutical Aspects of Some Anti-Glaucoma Drugs,bitors were essentially systemic drugs but recently new potent compounds have been described to be active after topical administration. Each class of drugs has a different pharmacokinetic behaviour due to the physico-chemical properties of the individual compounds. The dynamics of ocular fluids, esp
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Scintigraphic Evaluation of Polymeric Formulations for Ophthalmic Use,tly alters the kinetics of the system because of the small volume of the tear film. The technique of gamma scintigraphy has superceded x-ray studies in the investigation of restriction of the nasolacrimal duct. It is a small step from this routine clinical application to apply the technique to the s
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