Titlebook: Oncology; An Evidence-Based Ap Alfred E. Chang (Hugh Cabot Professor of Surgery a Book 2006 The Editor(s) (if applicable) and The Author(s)

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Jeffrey R. Skaar,James A. DeCaprio MDast accomplishments and future initiatives critical in fores.Forest canopies not only support high terrestrial biodiversity but also represent a critical interface between the atmosphere and the earth. They provide goods and services to support diverse human communities and offer opportunities to ex

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Michele Carbone MD, PhD,Giuseppe Barbanti-Brodano MDvide goods and services to support diverse human communities and offer opportunities to explore sustainable use of these resources for many generations of local livelihoods. Forest canopies are important carbon sequestration units, and in this sense, serve as climate control for the planet. Canopies

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Evidence-Based Approach to Oncologyiagnosis, and therapy, we hear, must be based on the best evidence to provide the best care. But is this approach new? And if it is, what have we been doing until now? In this chapter, we hope to provide perspectives on this question, by examining what evidence-based medicine (EBM)—oncology, in part

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Principles of Radiation Oncologygy in the 1930s and 1940s. Today, more than 50% of newly diagnosed cancer patients receive radiation therapy, typically as a part of curative combined modality treatment with surgery and/or chemotherapy. Additionally, a majority of patients who present with metastatic disease or who develop metastas

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Principles of Surgical Therapy in Oncology weapon in an armamentarium of oncologic therapies. As the role of surgery changes, so has the role of the surgeon, evolving from . to surgical oncologist. This role continues to evolve, as the management of cancer is altered by increased knowledge of genetics, molecular biology, and tumor immunolog

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Principles of Targeted and Biological Therapies and/or survival signaling pathways can become constitutively activated or deregulated in human cancers.1 Many studies have attempted to show that a given molecular change is the key event involved in the pathogenesis of a specific cancer. Such information may not only provide a better understanding

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Evaluation of Tumor Markers: An Evidence-Based Guide for Determination of Clinical Utilitydictable outcomes. In theory, if this separation is both reliable and disparate, one can apply therapy more efficiently to the population by exposing those most likely to need and benefit from the therapy while ensuring that the other group avoids needless toxicities. In essence, the term tumor mark