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Titlebook: Oncoimmunology; A Practical Guide fo Laurence Zitvogel,Guido Kroemer Book 2018 Springer International Publishing AG 2018 Cancer Immunothera

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书目名称Oncoimmunology
副标题A Practical Guide fo
编辑Laurence Zitvogel,Guido Kroemer
视频video
概述Sets out the main principles of oncoimmunology.Examines the latest advances and their implications for clinical practice.Focuses especially on drugs with FDA/EMA approvals and breakthrough status.Repr
图书封面Titlebook: Oncoimmunology; A Practical Guide fo Laurence Zitvogel,Guido Kroemer Book 2018 Springer International Publishing AG 2018 Cancer Immunothera
描述.In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals.. .Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hopethat this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field..
出版日期Book 2018
关键词Cancer Immunotherapy; Immuno-Oncology; Cancer Vaccines; Biomarkers; Immunopathology
版次1
doihttps://doi.org/10.1007/978-3-319-62431-0
isbn_softcover978-3-319-87310-7
isbn_ebook978-3-319-62431-0
copyrightSpringer International Publishing AG 2018
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https://doi.org/10.1007/978-3-319-62431-0Cancer Immunotherapy; Immuno-Oncology; Cancer Vaccines; Biomarkers; Immunopathology
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978-3-319-87310-7Springer International Publishing AG 2018
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Principles of Oncoimmunology,e first phase that lasts from antiquity to the eighties of the twentieth century, cancer was considered as a cellular disease resulting from the invasion of tissues by abnormal cells. Hence, the main challenge consisted in excising the tumor with its margins to make sure that all cancer cells had be
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The Human Tumor Microenvironmentished by surgery, which removes the primary tumor. Radiotherapy and conventional chemotherapies also aimed at targeting tumor cells preferentially. The high capacity of tumor cells to divide as compared to the normal cells makes them more sensitive to agents that physically, in the case of radiother
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CD8+ T Cells in Immunotherapy, Radiotherapy, and Chemotherapyent and execute tumor clearance by recognizing specific tumor-associated antigens (TAA) on cancer cells and mediating tumor cytotoxic activity. PD-L1 and PD-1 checkpoint blockade unleashes the effector function of CD8. T cells and results in significant objective response in patients with different
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Regulatory T Cells: Their Role, Mechanism of Action, and Impact on Cancerled to a revolution in the treatment of several solid tumors and hematologic malignancies. T cells upregulate expression of immune checkpoint receptors following prolonged antigen stimulation, and expression of these receptors is associated with T cell dysfunction. Monoclonal antibodies targeting cy
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