Titlebook: Oncogenes in B-Cell Neoplasia; Workshop at the Nati Michael Potter,Fritz Melchers,Martin Weigert Book 1984 The Editor(s) (if applicable) an

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Cloned Neoplastic B Cells Release a Growth Factor Which Augments Lymphokine-Mediated Proliferation o; Kaplan 1982; Bishop 1983). As a first step in identifying a putative B cell-derived autocrine growth factor, we have examined a series of neoplastic B cell clones which were derived from the ..-adapted BCL. cell line and were selected for their lack of spontaneous IgM secretion (Brooks 1983). Base

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T Cell Factors Regulating B Cell Activation and Differentiationbeen accelerated through the use of factors derived from T cell sources. T-B collaborations, previously attributed to cell to cell interaction, are mediated by these factors. T cells activated specifically or non-specifically in vitro secrete factors which induce proliferation of preactivated B cell

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Interleukin 3 Dependent Retrovirus Induced Lymphomas: Loss of the Ability to Terminally Differentiatole. In Moloney leukemia virus (MoLV) induced leukemia, one potential component is an immune response (Lee and Ihle, 1981; Lee and Ihle, 1981). This has been speculated to be due to a requirement to generate an appropriate target cell population, which is accomplished by viral antigen-induced produc

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Growth Regulation of a B-Cell Lymphoma via the Antigen Receptorence of anti-immunoglobulin reagents (Ralph, 1979; Boyd and Schrader, 1981). This growth arrest is rapid and complete: virtually all of the cells stop growing in approximately 20 hours of culture with stoichiometric amounts of anti-Ig (DeFranco et al., 1982a). In contrast, most other B-cell lines gr

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Interleukin-2 Receptors on Activated Malignant and Normal B-Cellssponses (Howard and Paul 1983). One such factor designated B-cell growth factor (BCGF) appears to be required for the proliferation of a subset of B cells following their interaction with antigen or with anti-immunoglobulin molecules. A second set of factors termed B-cell differentiation or T-cell r

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N. Glaichenhaus,C. Galup,E. Mougneau,F. Cuzin liegen. Dieses bietet einen willkommenen Anlaß, sich an den großen Beitrag . zur Entwicklung der Kerntechnik in Deutschland zu erinnern. Schon im Anfang des Jahres 1940 entwarf .) in zwei Arbeiten die Theorie des Kernreaktors, die schon die meisten der auch heute noch geltenden Erkenntnisse enthiel

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M.-A. Lane,H. A. F. Stephens,K. M. Doherty,M. B. Tobin liegen. Dieses bietet einen willkommenen Anlaß, sich an den großen Beitrag . zur Entwicklung der Kerntechnik in Deutschland zu erinnern. Schon im Anfang des Jahres 1940 entwarf .) in zwei Arbeiten die Theorie des Kernreaktors, die schon die meisten der auch heute noch geltenden Erkenntnisse enthiel

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