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Titlebook: Oncogenes and Tumor Suppressor Genes in Human Malignancies; Christopher C. Benz,Edison T. Liu Book 1993 Kluwer Academic Publishers 1993 DN

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Normal and malignant growth control by p53,2 years ago. Although the function of this protein is not yet known, p53 appears to be a critical protein involved in the regulation of cell growth. Once classified as a dominant oncogene [.–.], it has recently become clear that only mutant forms of p53 can contribute to cellular transformation [.–.
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Angiogenesis: A mechanism by which oncogenes and tumor suppressor genes regulate tumorigenesis, series of genetic lesions that activate proto-oncogenes to oncogenes and that inactivate tumor suppressor genes, sometimes called anti-oncogenes [.]. About 50 oncogenes and a dozen anti-oncogenes have been cloned and sequenced. The functions of most of them are well understood in the sense that the
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Kaposi sarcoma: A cytokine-responsive neoplasia?,bed [.–.], Kaposi sarcoma still affects nearly 30% of patients at some time during their disease course. Since both the extent of disease and rate of progression varies widely between patients [.], cytokines are hypothesized to be involved in the pathogenesis of this neoplasia [.–.].
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https://doi.org/10.1007/978-1-4615-3088-6DNA; angiogenesis; cell; metastasis; tumor; tumorigenesis
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Oncogenes and Tumor Suppressor Genes in Human Malignancies978-1-4615-3088-6Series ISSN 0927-3042 Series E-ISSN 2509-8497
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