| 书目名称 | Oncogenes Meet Metabolism |
| 副标题 | From Deregulated Gen |
| 编辑 | G. Kroemer,D. Mumberg,K. Petersen |
| 视频video | |
| 丛书名称 | Ernst Schering Foundation Symposium Proceedings |
| 图书封面 |  |
| 描述 | .In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).. |
| 出版日期 | Conference proceedings 2008 |
| 关键词 | Biomarkers; Cancer Research; Metabolic Profiling; Metabonomics; Warburg Effect; cells; diagnostics; physiol |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-540-79478-3 |
| isbn_softcover | 978-3-642-09840-6 |
| isbn_ebook | 978-3-540-79478-3Series ISSN 0947-6075 |
| issn_series | 0947-6075 |
| copyright | Springer-Verlag Berlin Heidelberg 2008 |
发表于 2025-3-21 19:01:23
