Titlebook: Oncogenes; An Introduction to t Kathy B. Burck,Edison T. Liu,James W. Larrick Book 1988 Springer-Verlag New York Inc. 1988 Chromosom.DNA.ca

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Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campai

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Introduction, central concept of proto-oncogenes and oncogenes: normal cellular genes (proto-oncogenes) controlling growth, development, and differentiation that somehow become misdirected (i.e. converted to oncogenes) in the neoplastic cancer cell.

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Oncogene Paradigm: Contribution to a Fundamental Understanding of Malignancy,A. Because cancer is characterized by loss of this normal control, we can at least begin to define and understand malignancy in molecular terms. The oncogene concept provides us with a reasonable molecular “handle” with which to deal with cancer.

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Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D.

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