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Titlebook: Of Fish, Fly, Worm, and Man; Lessons from Develop Christiane Nüsslein-Volhard,Jörn Krätzschmar Conference proceedings 2000 Springer-Verlag

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Interactions Between Wingless and Frizzled Molecules in Drosophila,enes found to control normal growth but to cause cancerous growth when misregulated. One of the best examples is the Wnt gene family. We will summarize our current view of how Wnt proteins signal, and the evidence that proteins of the Frizzled (Fz) family mediate Wnt signaling by acting as specific cell surface receptors.
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,Presenilin Proteins and Their Function During Embryonic Development and Alzheimer’s Disease,C-terminus (γ-secretase) of Aβ (Haass and Selkoe 1993; Fig. 1). Aβ is produced under physiological conditions in cultured cells and is secreted into the media. In vivo, Aβ is detected in human plasma and cerebrospinal fluid (Haass and Selkoe 1993).
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Eph Receptors and Ephrins Are Key Regulators of Morphogenesis,xon guidance in the developing nervous system, neural crest migration and segmentation of the paraxial mesoderm and the hindbrain region of the neural plate. This review outlines the evidence for these conclusions and focuses mainly, but not exclusively, on the role of Eph/ephrin signalling in the nervous system.
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Conference proceedings 2000mong them the genome sequences of Drosophila melanogaster and the human. With these achievements, the stage is set for the next phase of "large-scale" biology, the study of the function of genes and the interactions between their protein products. The aim of the Ernst Schering Research Foundation Wo
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The Heterotrimeric G Protein Genes of Caenorhabditis elegans,ene function involves the determination of expression patterns, and the description of loss-of-function as well as gain-of-function phenotypes. We performed such studies for the complete family of G protein α subunits.
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