书目名称 | Nuclear Receptors | 副标题 | Methods and Experime | 编辑 | Mostafa Z. Badr | 视频video | | 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | This volume presents valuable techniques for studying the class of ligand-activated transcription factors known as nuclear receptors. After a brief overview of the history of the field, chapters cover methods to detect the receptors and their mRNAs in various tissues, protocols to characterize nuclear receptor modulators and activities, their signaling and roles in certain pathogenesis, molecular modeling of nuclear receptor-ligand interactions, as well as the utility of informatics in the field of nuclear receptors. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and cutting-edge, .Nuclear Receptors: Methods and Experimental Protocols .seeks to aid researchers working toward furthering ourunderstanding of these vital receptors and their role in numerous pathological conditions.. | 出版日期 | Book 2019 | 关键词 | Drug discovery; NR ligands; Ligand-activated transcription factors; Receptor signaling; Molecular modeli | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-9195-2 | isbn_ebook | 978-1-4939-9195-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2019 |
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