| 书目名称 | Nrf2 and its Modulation in Inflammation | | 编辑 | Huai Deng | | 视频video | | | 概述 | Provides a comprehensive and up-to-date account of Nrf2 research.Brings together mechanistic understanding and phenotypical/clinical knowledge about Nrf2.Covers role of Nrf2 in the immune response dur | | 丛书名称 | Progress in Inflammation Research | | 图书封面 |  | | 描述 | .Nrf2, a transcription factor that mediates transcriptional responses to oxidative and xenobiotic stresses, plays a central role in cellular protection against internal or external toxins. Defects in Nrf2 and the relevant regulatory pathways are associated with a number of pathologies including inflammation, respiratory diseases, cardiovascular dysfunctions, metabolic syndrome and diabetes, neurodegeneration, and cancer. This book comprehensively reviews the up-to-date discoveries for the roles of Nrf2 in several human diseases in the context of inflammation. In particular, the molecular mechanisms that mediate the functions of Nrf2 and its interacting network in inflammation and pathogenesis are explicated. In addition, the research and therapeutic applications of Nrf2-targeting compounds in different diseases were summarized. This book is expected to be a valuable reference for worldwide researchers conducting both mechanistic and therapeutic studies of Nrf2 and relevant factors... . | | 出版日期 | Book 2020 | | 关键词 | chronic inflammation; inflammatory mediators; molecular mechanisms; oxidative stress response; therapeut | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-030-44599-7 | | isbn_ebook | 978-3-030-44599-7Series ISSN 1422-7746 Series E-ISSN 2296-4525 | | issn_series | 1422-7746 | | copyright | Springer Nature Switzerland AG 2020 |
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发表于 2025-3-21 20:09:33
