Titlebook: Nrf2 and its Modulation in Inflammation; Huai Deng Book 2020 Springer Nature Switzerland AG 2020 chronic inflammation.inflammatory mediato

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Nrf2 and its Modulation in Inflammation978-3-030-44599-7Series ISSN 1422-7746 Series E-ISSN 2296-4525

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Nrf2 in Immune Responses During Inflammation,ponses, immune surveillance, and immune response in inflammatory diseases, and experimental models of disease. We also summarize the consequences of the deficiency or deregulation of Nrf2 axis and how they are related to the development and aggravation of diseases.

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Nrf2 and Inflammation-Triggered Carcinogenesis,book chapter, we highlight the role of Nrf2 in various types of cancers describing Nrf2 signaling in inflammation and oxidative stress to support either cancer cell survival or death. Current status of Nrf2 as a target in cancer therapy is also discussed.

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Molecular Mechanisms of Nrf2 in Inflammation: Interactions Between Nrf2 and Inflammatory Mediators,g genes coding for proinflammatory cytokines. In this chapter, we summarize and discuss the direct and indirect role of Nrf2 in the regulation of inflammatory response and the development of therapeutic targets by identifying new molecular mechanisms.

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