| 书目名称 | Novel Chemical Tools to Study Ion Channel Biology |
| 编辑 | Christopher Ahern,Stephan Pless |
| 视频video | |
| 概述 | Captures the diversity of chemical biology techniques currently available and describes their application to model ion channel and transmembrane receptor systems.Covers a wide array of experimental ap |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | .This volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environment; the modification of engineered cysteine side chains, including cysteine scanning mutagenesis and the attachment of fluorescent probes and bio-reactive tethers; and the nascent use of genetic code expansion, evaluating its applications to ion channel and membrane proteins. This comprehensive text provides multifaceted perspectives on the great diversity of state-of-the-art methods which take advantage of the ever-expanding chemical toolbox to study ion channel biology..Capturing the contributions and innovations of renowned laboratory researchers in transmembrane protein study for the first time, this book is comprehensive in scope. It covers a wide array of experimental approaches: photochemistry, novel biological tools, and innovative spectroscopy, all combined with traditional techniques of electrophysiology and molecular biology. .Novel Chemical Tools to Study Ion Channel Biology., part of the bestselling .Advances in Experimental Medicine |
| 出版日期 | Book 2015 |
| 关键词 | Biophysics; Bioreactivity; Fluorometry; Ion Channels; Modifications; Proteins |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4939-2845-3 |
| isbn_softcover | 978-1-4939-4762-1 |
| isbn_ebook | 978-1-4939-2845-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
发表于 2025-3-21 17:24:36
