书目名称 | Notch Signaling in Embryology and Cancer | 副标题 | Molecular Biology of | 编辑 | Jörg Reichrath,Sandra Reichrath | 视频video | | 概述 | The content is presented in a logical and coherent structure, enabling the reader to readily access relevant information.The volume editors are renowned experts on Notch and Notch Signaling and the ch | 丛书名称 | Advances in Experimental Medicine and Biology | 图书封面 |  | 描述 | .This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. .Taken as a whole, with its companion books – .Notch Signaling in Embryology. and .Notch Signaling in Cancer. – this is a definitive discussion of the | 出版日期 | Book 2020Latest edition | 关键词 | Notch; Notch Signaling; Embryology; Microbiome and Cancer; Notch and senescence; Regulation of Notch Sign | 版次 | 2 | doi | https://doi.org/10.1007/978-3-030-36422-9 | isbn_softcover | 978-3-030-36424-3 | isbn_ebook | 978-3-030-36422-9Series ISSN 0065-2598 Series E-ISSN 2214-8019 | issn_series | 0065-2598 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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