Titlebook: Non-coding RNAs in Colorectal Cancer; Ondrej Slaby,George A. Calin Book 2016 The Editor(s) (if applicable) and The Author(s), under exclus

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Involvement of Non-coding RNAs in Chemo- and Radioresistance of Colorectal Cancerctal cancer (CRC) cells to chemo- and radiotherapy represents the main hurdle to the successful treatment, leading to tumor recurrence and, consequently, a poor prognosis. Therefore, overcoming drug and radiation resistance, enhancing drug and radiation sensitivity of CRC cells, and improving the ef

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Book 2016ion of therapeutic response. ..The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology. .

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MicroRNA Methylation in Colorectal Cancerregulated miRNAs in CRC, which are regulated by CpG island hypermethylation and DNA hypomethylation. In addition, aberrant DNA methylation of miRNA genes holds a great promise in several clinical applications such as biomarkers for early screening, prognosis, and therapeutic applications in CRC.

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Circulating Non-coding RNA as Biomarkers in Colorectal Cancerarker and could deliver insight into the disease process. This chapter addresses the recent discoveries on circulating microRNA and long non-coding RNA as diagnostic or prognostic biomarkers in colorectal cancer.

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Book 2016-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. ..This work further provides the comprehensive overview and novel insights into u

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