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Titlebook: Non-Viral Gene Delivery Vectors; Methods and Protocol Gabriele Candiani Book 2016 Springer Science+Business Media New York 2016 conventiona

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From Artificial Amino Acids to Sequence-Defined Targeted Oligoaminoamideslp of these oligoamino acids multifunctional nucleic acid (NA) carriers can be designed and produced in highly defined topologies. Here we describe the synthesis of the artificial oligoamino acid Fmoc-Stp(Boc.)-OH, the subsequent assembly into sequence-defined oligomers and the formulation of tumor-targeted plasmid DNA (pDNA) polyplexes.
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Lipoplexes from Non-viral Cationic Vectors: DOTAP-DOPE Liposomes and Gemini Micellesre promising transfection agents and do not suffer from limitations related to toxicity and immunogenic effects. In particular, lipid-based aggregates are generally considered biocompatible and versatile nanocarriers whose composition can be designed to include a cationic molecule which ensures stro
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Targeted Delivery of Peptide-Tagged DNA Lipoplexes to Hepatocellular Carcinoma Cells corrective gene therapy for the treatment of neoplasms and other disorders of a genetic origin. Here, a step-wise account of the assembly and characterization of hepatocellular carcinoma cell-specific DNA lipoplexes and their cytotoxicity assessment in and delivery to the human hepatocellular carci
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