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Titlebook: Nitroarenes; Occurrence, Metaboli Paul C. Howard,Stephen S. Hecht,Frederick A. Belan Book 1990 Springer Science+Business Media New York 199

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书目名称Nitroarenes
副标题Occurrence, Metaboli
编辑Paul C. Howard,Stephen S. Hecht,Frederick A. Belan
视频video
丛书名称Environmental Science Research
图书封面Titlebook: Nitroarenes; Occurrence, Metaboli Paul C. Howard,Stephen S. Hecht,Frederick A. Belan Book 1990 Springer Science+Business Media New York 199
描述Prior to 1979, consideration of the problem of the carcinogenicity of the aromatic amine class of chemicals took place primarily in poster sessions and symposia of annual meetings of the American Association for Cancer Research and analogous international associations. In November 1979 the first meeting concerned with the aromatic amines was held in Rockville, Haryland under primary sponsorship of the National Cancer Institute. The proceedings from this meeting were published as Monograph 58 of the Journal of the National Cancel‘ Institute in 1981. The second meeting in this series, the Second International Conference on N-Substituted Aryl Compounds, was held in March/April of 1982 in Hot Springs, Arkansas. The National Cancer Institute and The National Center for Toxicological Research were the primary sponsors of this meeting. The proceedings were published as Volume 49 of the journal En-vil‘onmental Health Perspectives in 1983. The third meeting in this series was held in April of 1987 at the Dearborn Hyatt in Dearborn, Michigan. The principal sponsor of this meeting was the Heyer L. Pre ntis Comprehensive Cancer Center of Metropolitan Detroit. The proceedings, Carcinogenic and
出版日期Book 1990
关键词DNA; Oxidation; RNA; air pollution; amines; bonding; chemicals; chemistry; environment; health; metabolism; mut
版次1
doihttps://doi.org/10.1007/978-1-4615-3800-4
isbn_softcover978-1-4613-6694-2
isbn_ebook978-1-4615-3800-4
copyrightSpringer Science+Business Media New York 1990
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Metabolism of 1-Nitropyrene Oxides and Effect of Nitrogen Dioxide on Arene Activationnd Shudo, 1985; Mitchell, 1988), it has been reported recently to be a minor adduct in rabbits and rats (Gallagher et al., 1988; Roy et al., 1989). Therefore, oxidative or oxidative-reductive metabolic pathways may be quantitatively more important .
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essions and symposia of annual meetings of the American Association for Cancer Research and analogous international associations. In November 1979 the first meeting concerned with the aromatic amines was held in Rockville, Haryland under primary sponsorship of the National Cancer Institute. The proc
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Interpretation of Carcinogenicity and Effective Dose in Chronic Exposures of Rats to High Diesel Exhry carcinogen in rats whenever these animals are chronically exposed to high diesel exhaust concentrations, and diesel soot is actually the indispensible component in the exhaust emission necessary to induce the tumors (Heinrich et al., 1986).
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Mutagenesis Induced by a Single Acetylaminofluorene Adduct Within the NarI Site is Position Dependenevent, we constructed double stranded plasmid molecules containing a single AAF bound to one of the three guanine positions. Using these plasmids, we found that only AAF bound to G. induces a -2 frameshift mutation event in SOS induced bacteria. This result is discussed in terms of local DNA conformation.
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