Titlebook: Nisoldipine 1987; P. G. Hugenholtz,J. Meyer Conference proceedings 1987Latest edition Springer-Verlag Berlin Heidelberg 1987 angina pector

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Membrane Potential and Nisoldipine Block of Calcium Channels in the Heart: Interactions with Channelpen time of the channels [5]. However, even the activity of this group of drugs depends on membrane potential, and at positive voltages the agonists can promote antagonist-like effects [18]. We are presently investigating the mechanisms behind these voltage-dependent actions. Our experiments are des

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Effect of Prolonged Treatment with Nisoldipine on Cholesterol Deposition and Cardiac Noradrenaline Rline (3.85 ± 0.30 μg/g dry wt for placebo controls: 0.87 ± 0.06 μg/g dry wt for the verapamil group)..Male New Zealand white cross rabbits were maintained on a high-cholesterol diet (2%) for 8 weeks. Half of the rabbits received nisoldipine (10 mg/kg body weight per day, incorporated in the diet). P

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Plasma Level-Effect Relationships for some Acute Cardiovascular Effects of Nisoldipine and Other Dih FBF responses to the dihydropyridines were directly dependent on the drug levels in plasma. In fact, the drug level-response curves did not show any hysteresis effect and obeyed Hill’s equation. The results show that the dihydropyridines differ predominantly with respect to their potencies in dilat

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Effect of Nisoldipine on Variant Anginasoldipine was effective in the first treatment period. In the two cases which did not have sufficient response to the group 2 therapy, the time of administration was changed in the second treatment period. After this, nisoldipine was effective in all cases in the second treatment period, including a

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Hemodynamic Effects of Intravenous Nisoldipine (−36%) and coronary (−25%) vascular resistance with an increase in heart rate (+20%) and cardiac index (CI) (+35%). Over the 30-min observation period there was a trend for all variables to return to control values although all but CVR and CSBF remained significantly different..The results obtained