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Titlebook: Nicotinic Receptors; Robin A.J. Lester Book 2014 Springer Science+Business Media New York 2014 behavior.disease.molecular structure.subtyp

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Nicotinic Receptors in the Spinal Cord,e dorsal horn, but pre- and postsynaptic nAChRs are found all over the spinal cord. The subunit composition of the spinal nAChRs is very diverse: α4β2* and α7 nAChRs are the most frequent subtypes, but evidence exists for the presence of α3*, α6*, and β4* receptors. Many neurons bear multiple subtyp
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Slow Synaptic Transmission in the Central Nervous System, nervous system (CNS). Slow nicotinic responses have been reported in the interpeduncular nucleus, hippocampus, neocortex, striatum, spinal cord, and thalamus. Studies have suggested that α4β2 containing nicotinic receptors may be the receptor subtype mediating the slow nicotinic synaptic events. Th
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The Effects of Nicotine on Learning and Memory, the effects of tobacco on learning and other cognitive processes. The capacity of nicotine to alter learning and cognition may facilitate the development and maintenance of nicotine addiction. Nicotine may enhance the formation of strong but yet maladaptive drug-stimuli associations that can trigge
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Nicotinic Receptors as Targets for Novel Analgesics and Anti-inflammatory Drugs,roughout the central and peripheral nervous system as well as immune cells. Despite encouraging results with many selective α4β2* agonists in animal models of pain, human studies showed a narrow therapeutic window between analgesic efficacy and toxicity is associated with the use of these agonists a
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