Titlebook: Nicotinic Acetylcholine Receptor Technologies; Ming D. Li Book 2016 Springer Science+Business Media New York 2016 nAChR subunits.nicotinic

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,Spectral Confocal Imaging to Examine Upregulation of Nicotinic Receptor Subunits in α4-Yellow Fluor the field of biology. In conjunction with gene targeting approaches, the insertion of color variants of fluorescent protein genes in cell-specific promoters have given neuroscientists rich information on the neuronal circuitry and localization of specific neurons within the CNS. However, the locali

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,α7-Nicotinic Acetylcholine Receptors: New Therapeutic Avenues in Alzheimer’s Disease,cal hallmark is the loss of cholinergic markers, associated with a reduction in the α7 subunit of the nicotinic acetylcholine receptor (nAChR) in the brains of AD patients. The α7-nAChR plays an important role in circuits involved in learning and memory, and may be a promising target for the treatme

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,α7-Nicotinic Acetylcholine Receptors and β-Amyloid Peptides in Alzheimer’s Disease,(Aβ), neurofibrillary tangles originating from hyperphosphorylated tau protein and neuronal loss preferentially affecting cholinergic neurons. Mutations in the amyloid precursor protein (APP), presenilin 1, or presenilin 2 genes are autosomal dominant causes of familial AD (FAD); the ε4 allele of th

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Evolutionary Relationship of Nicotinic Acetylcholine Receptor Subunits in Both Vertebrate and Invernary relationship and biological functions for most of these subunits are largely unknown. The purposes of this chapter were (1) to infer molecular evolutionary history and divergence times of nAChRs, (2) to identify possible essential amino acid residues for the complementary component of the acety

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Kristin M. Ackerman,R. Thomas Boyd,000 km., where the only arable land is found. The large areas of the Sahara Desert are sparsely inhabited. About half of Egypt’s residents live in urban areas, with most people spread across the densely populated centers of greater Cairo, Alexandria and other major cities in the Nile Delta. Egypt’s

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