Titlebook: Nicotine and Related Alkaloids; Absorption, distribu J. W. Gorrod,J. Wahren Book 1993 Springer Science+Business Media Dordrecht 1993 Oxidat

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Terminal

https://doi.org/10.1007/978-94-011-2110-1Oxidation; absorption; alkaloids; enzyme; enzymes; kinetics; metabolism; methylation; pharmacokinetics; resea

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N-Oxidation, N-methylation and N-conjugation reactions of nicotine, of sp. hybridization on base strength, since as the ‘s’ character of an orbital increases, the electrons in that orbital are bound more tightly to the nucleus. In this respect, the regiospecificity of N-oxidation is an important consideration, especially as it relates to the structural and chemical

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Physiologically based pharmacokinetic modelling of nicotine,PK approach and the availability of adequate computer hardware and software. In recent years, however, PBPK modelling has become a practical tool for the study of a variety of pharmacological and toxicological problems (Bischoff ., 1971; Gerlowski and Jain, 1983).

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New methods for probing the disposition of nicotine in humans,y and pharmacology of nicotine. It is noteworthy that literature is almost totally, devoid of information concerning the influence of disease on the pharmacokinetics of nicotine. Thus, data with regard to the influence of, e.g. liver disease or renal disease on nicotine disposal are not available bu

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ainability challenges ofmajor agroecosystems in the developing and industrialized worlds. Theconcluding chapter discusses the design and implementation of sustainabledevelopment pathways, through the expression978-3-030-34601-0978-3-030-34599-0Series ISSN 2662-3889 Series E-ISSN 2662-3897

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